summarize
(2-chloro-5-iodophenyl)[4-[[(3S) -tetrahydro-3-furanyl] oxy] phenyl] ketone belongs to the ketone organic matter, is a pharmaceutical intermediate, can be used to prepare Cchemicalbook-aryl glucoside SGLT2 inhibitors with the following general formula. This product is an intermediate of Empalizine, a potent and selective SGLT-2 inhibitor that improves blood glucose control syndrome in diabetic rats.
Apply:
(2-chloro-5-iodophenyl)[4-[[(3S) -tetrahydro-3-furanyl] oxy] phenyl] ketone belongs to the ketone organic group and can be used to prepare C-aryl glucoside SGLT2 inhibitors with the following general formula. SGLT2 is the major NChemicalbooka+/ glucose cotransporter in proximal tubule S1 epithelial cells and is responsible for 90% of glucose reabsorption in the kidney. SGLT2 inhibitors inhibit renal glucose reabsorption and enable diabetic patients to achieve normal plasma glucose levels through urinary glucose excretion, thereby increasing insulin sensitivity and delaying the development of diabetes complications.
| Fusing point: |
109-113oC |
| Boiling point: |
526ºC |
| density: |
1.639 |
| Storage condition: |
under inert gas (nitrogen or Argon) at 2-8 °C |
| solubility: |
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| form: |
Solid |
| colour: |
Off-White to Pale Beige |
| Flash point: |
272ºC |
Installation Instructions
Jiangsu Boquan Biotechnology Co., LTD. (hereinafter referred to as "Boquan") is a long-term engaged in fine chemical products and set production, sales and service in one of the company, the products are widely used in fine chemical raw materials, organic synthesis and pharmaceutical industry, chemical reagents, industrial sewage treatment, cosmetics, industrial electroplating, daily chemicals, food additives, pesticide chemical industry and other industries. Products are distributed all over the world, trusted by customers. The company's integrity, strength and product quality are widely recognized by the majority of customers and the industry. In terms of service, our company adheres to the principle of customer first, pursues the concept of "high quality, excellent price, and thoughtful service", and is committed to providing customers with quality products and pleasant shopping experience, no matter the size of customer demand, we can supply. In line with the principle of high quality, high efficiency and high service, we enjoy a good reputation in the same industry, and have a good reputation and influence, thanks to the support and love of manufacturers and customers.
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