Purpose:
1.Diethyl pyrocarbonate is an organic ester compound, which can be used as a modification reagent for His and Tyr residues in proteins. Durable probes for structural splitting in dsDNA that react partially or fully with nonstacking bases; "They are used as antimicrobial additives, ribonuclease inhibitors, histidine residue modifiers, and as reagents for the conversion of imines to carbamates."
2.Diethyl pyrocarbonate can be used for RNA extraction in biological experiments.
3."It is an ester compound that can be used as a modification agent of diethyl pyrocarbonate protein histidine and tyrosine, and is also a chemical modifier of ribonuclease. It reacts with the imidazole ring of the active group histidine of ribonuclease and inhibits ribonuclease activity."
Point of melting: |
69ºC |
Boiling point: |
93-94 °C18 mm Hg(lit.) |
Density of density: |
1.12 g/mL at 20 °C |
Index of refraction: |
n20/D 1.398(lit.) |
Point of flash: |
157 °F |
Storage conditions: |
2-8°C |
Degree of solubility: |
95% ethanol: soluble, 4.5g/10mL, transparent, colorless |
form: |
liquid,APHA:≤20 |
Solubility of water: |
slow decomposition |
Sensitivity: |
Moisture Sensitive |
stability: |
Flammable. Unstable - easily dissolves. Incompatible with strong oxidants, strong acids, strong reducing agents, strong bases and ammonia. |
LogP: |
1.101 (est) |